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Publications

Jojoa-Cruz S, Saotome K, Tsui CCA, Lee WH, Sansom MSP, Murthy SE*, Patapoutian A*, Ward AB*. Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun. 2022 Feb 14;13(1):850. 

Procko C*, Murthy SE*, Keenan WT, Mousavi SAR, Dabi T, Coombs A, Procko E, Baird L, Patapoutian A, Chory J. Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants. Elife. 2021 Mar 16;10.  

Murthy SE, Dubin AE, Whitwam T, Jojoa-Cruz S, Cahalan SM, Mousavi SAR, Ward AB, Patapoutian A. (2018 ) OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels. Elife 7:e41844.

 

Jojoa-Cruz S*, Saotome K*, Murthy SE, Tsui CCA, Sansom MS, Patapoutian A, Ward AB. (2018) Cryo-EM structure of the mechanically activated ion channel OSCA1.2. Elife 7:e41845.

 

Murthy SE, Loud MC, Daou I, Marshall KL, Schwaller F, Kühnemund J, Francisco AG, Keenan WT, Dubin AE, Lewin GR, Patapoutian A. (2018) The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice. Science Transl. Med. 10(462):eaat9897.

 

Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB. (2018) Structure of the mechanically activated ion channel Piezo1. Nature 554(7693):481-486.

 

Coste B*, Murthy SE*, Mathur J, Schmidt M, Mechioukhi Y, Delmas P, Patapoutian A. (2015) Piezo1 ion channel pore properties are dictated by C-terminal region. Nature Commun. 6:7223.

 

Albuisson J*, Murthy SE*, Bandell M, Coste B, Louis-Dit-Picard H, Mathur J, Fénéant-Thibault M, Tertian G, de Jaureguiberry JP, Syfuss PY, Cahalan S, Garçon L, Toutain F, Simon Rohrlich P, Delaunay J, Picard V, Jeunemaitre X, Patapoutian A. (2013) Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels. Nature Commun. 4:1884.

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